Just made an layout image to see how the Vita screen could fit an DS game with its 544p screen without needing bilinear filtering on anything related. Seems it would work nice
PlayStation Vita - Wikipedia
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新着 psvita+ソフト2本 携帯用ゲーム本体 - bennettheymanlaw.com
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Buy Desmume Ps Vita | UP TO 50% OFF
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HEN_Emulator] DeSmuME MasterFeizz's edition - PS Vita CFW & Homebrew - psXtools.de Community