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Jít na procházku vejce choulostivé overall mutation load vs incidence of p53 mutations Legrační cena zahynout

The function of a heterozygous p53 mutation in a Li-Fraumeni syndrome  patient | PLOS ONE
The function of a heterozygous p53 mutation in a Li-Fraumeni syndrome patient | PLOS ONE

Clinical implications of subclonal TP53 mutations in acute myeloid leukemia  | Haematologica
Clinical implications of subclonal TP53 mutations in acute myeloid leukemia | Haematologica

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene

Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune  escape through PHLPP2/AKT/PD-L1 pathway
Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway

Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion -  ScienceDirect
Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion - ScienceDirect

TP53 Mutation as Potential Negative Predictor for Response of Anti-CTLA-4  Therapy in Metastatic Melanoma - eBioMedicine
TP53 Mutation as Potential Negative Predictor for Response of Anti-CTLA-4 Therapy in Metastatic Melanoma - eBioMedicine

Activating STING1-dependent immune signaling in TP53 mutant and wild-type  acute myeloid leukemia | PNAS
Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia | PNAS

Life and Death Decision-Making by p53 and Implications for Cancer  Immunotherapy: Trends in Cancer
Life and Death Decision-Making by p53 and Implications for Cancer Immunotherapy: Trends in Cancer

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Survival of patients with p53 mutations in the DNA-binding motifs... |  Download Scientific Diagram
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram

Impact of TP53 mutations in Triple Negative Breast Cancer | npj Precision  Oncology
Impact of TP53 mutations in Triple Negative Breast Cancer | npj Precision Oncology

An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by  acetylation | Science Advances
An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation | Science Advances

Frequency of p53 mutations in human cancers. (A) Schematic picture... |  Download Scientific Diagram
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram

LRP1B or TP53 mutations are associated with higher tumor mutational burden  and worse survival in hepatocellular carcinoma
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma

IJMS | Free Full-Text | The Therapeutic Potential of the Restoration of the  p53 Protein Family Members in the EGFR-Mutated Lung Cancer
IJMS | Free Full-Text | The Therapeutic Potential of the Restoration of the p53 Protein Family Members in the EGFR-Mutated Lung Cancer

Frontiers | Association Analyses of TP53 Mutation With Prognosis, Tumor Mutational  Burden, and Immunological Features in Acute Myeloid Leukemia
Frontiers | Association Analyses of TP53 Mutation With Prognosis, Tumor Mutational Burden, and Immunological Features in Acute Myeloid Leukemia

Targeting a neoantigen derived from a common TP53 mutation | Science
Targeting a neoantigen derived from a common TP53 mutation | Science

Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with  the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes

TP53 alterations of hormone-naïve prostate cancer in the Chinese population  | Prostate Cancer and Prostatic Diseases
TP53 alterations of hormone-naïve prostate cancer in the Chinese population | Prostate Cancer and Prostatic Diseases

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

Pathogenesis of TP53-mutated Acute Myeloid leukemia | Laboratory of Daniel  C. Link, M.D. | Washington University in St. Louis
Pathogenesis of TP53-mutated Acute Myeloid leukemia | Laboratory of Daniel C. Link, M.D. | Washington University in St. Louis

Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral  and Cell-Based Immunotherapies
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

Cancers | Free Full-Text | Influence of TP53 Mutation on Survival of  Diffuse Large B-Cell Lymphoma in the CAR T-Cell Era
Cancers | Free Full-Text | Influence of TP53 Mutation on Survival of Diffuse Large B-Cell Lymphoma in the CAR T-Cell Era

The TP53 mutation rate differs in breast cancers that arise in women with  high or low mammographic density | npj Breast Cancer
The TP53 mutation rate differs in breast cancers that arise in women with high or low mammographic density | npj Breast Cancer

Homogenous TP53mut-associated tumor biology across mutation and cancer  types revealed by transcriptome analysis | Cell Death Discovery
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery

TP53/BRAF mutation as an aid in predicting response to immune-checkpoint  inhibitor across multiple cancer types | Aging
TP53/BRAF mutation as an aid in predicting response to immune-checkpoint inhibitor across multiple cancer types | Aging