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Synthesis of α-Alkylated Ketones via Selective Epoxide Opening/Alkylation Reactions with Primary Alcohols | Organic Letters
![SOLVED: The following reaction sequence gives an epoxide as the major final product: NaOEt EtOH, heat 2) HzO2 NaOH a) Propose a complete mechanism to explain the transformation. b) The starting material SOLVED: The following reaction sequence gives an epoxide as the major final product: NaOEt EtOH, heat 2) HzO2 NaOH a) Propose a complete mechanism to explain the transformation. b) The starting material](https://cdn.numerade.com/ask_images/ceee929ae5e44d7e9e04d8815f6e5685.jpg)
SOLVED: The following reaction sequence gives an epoxide as the major final product: NaOEt EtOH, heat 2) HzO2 NaOH a) Propose a complete mechanism to explain the transformation. b) The starting material
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Synthesis of α-Alkylated Ketones via Selective Epoxide Opening/Alkylation Reactions with Primary Alcohols | Organic Letters
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Regioselective Carbonylation of 2,2-Disubstituted Epoxides: An Alternative Route to Ketone-Based Aldol Products | Journal of the American Chemical Society
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Selective rearrangement of terminal epoxides into methylketones catalysed by a nucleophilic rhodium–NHC–pincer complex - Chemical Communications (RSC Publishing) DOI:10.1039/C4CC07154A
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Synthesis of α-Alkylated Ketones via Selective Epoxide Opening/Alkylation Reactions with Primary Alcohols | Organic Letters
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