Roles of the endoplasmic reticulum–resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease
![Targeting HSP47 and HSP70: promising therapeutic approaches in liver fibrosis management | Journal of Translational Medicine | Full Text Targeting HSP47 and HSP70: promising therapeutic approaches in liver fibrosis management | Journal of Translational Medicine | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12967-022-03759-z/MediaObjects/12967_2022_3759_Fig1_HTML.png)
Targeting HSP47 and HSP70: promising therapeutic approaches in liver fibrosis management | Journal of Translational Medicine | Full Text
![HSP47 as a collagen-specific molecular chaperone: function and expression in normal mouse development - ScienceDirect HSP47 as a collagen-specific molecular chaperone: function and expression in normal mouse development - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S108495210300082X-gr3.jpg)
HSP47 as a collagen-specific molecular chaperone: function and expression in normal mouse development - ScienceDirect
Schematic representation of the possible functions of Hsp47. Hsp47 is... | Download Scientific Diagram
![Roles of the endoplasmic reticulum–resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease - Journal of Biological Chemistry Roles of the endoplasmic reticulum–resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease - Journal of Biological Chemistry](https://www.jbc.org/cms/asset/e517050b-9914-49b6-8696-0c632072da39/gr1.jpg)
Roles of the endoplasmic reticulum–resident, collagen-specific molecular chaperone Hsp47 in vertebrate cells and human disease - Journal of Biological Chemistry
![A BRET-based assay reveals collagen–Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction - ScienceDirect A BRET-based assay reveals collagen–Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0021925820304567-gr4.jpg)
A BRET-based assay reveals collagen–Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction - ScienceDirect
![Model for Hsp47 function in collagen maturation in vivo. (A) Wild-type... | Download Scientific Diagram Model for Hsp47 function in collagen maturation in vivo. (A) Wild-type... | Download Scientific Diagram](https://www.researchgate.net/publication/7253367/figure/fig6/AS:340529289154564@1458199917457/Model-for-Hsp47-function-in-collagen-maturation-in-vivo-A-Wild-type-cell-B.png)
Model for Hsp47 function in collagen maturation in vivo. (A) Wild-type... | Download Scientific Diagram
![Fibroblast Marker (Vimentin, alpha smooth muscle Actin, Hsp47, S100A4) Antibody Panel - Human, Mouse (ab254015) Fibroblast Marker (Vimentin, alpha smooth muscle Actin, Hsp47, S100A4) Antibody Panel - Human, Mouse (ab254015)](https://www.abcam.com/ps/products/254/ab254015/Images/ab254015-344809-fibroblast-marker-antibody-panel-EPR3776-immunohistochemistry-cervical-carcinoma-human.jpg)
Fibroblast Marker (Vimentin, alpha smooth muscle Actin, Hsp47, S100A4) Antibody Panel - Human, Mouse (ab254015)
![HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41388-020-1311-7/MediaObjects/41388_2020_1311_Fig4_HTML.png)
HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene
![Ancestry & molecular evolutionary analyses of heat shock protein 47 kDa ( HSP47/SERPINH1) | Scientific Reports Ancestry & molecular evolutionary analyses of heat shock protein 47 kDa ( HSP47/SERPINH1) | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-017-10740-0/MediaObjects/41598_2017_10740_Fig1_HTML.jpg)
Ancestry & molecular evolutionary analyses of heat shock protein 47 kDa ( HSP47/SERPINH1) | Scientific Reports
![HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41388-020-1311-7/MediaObjects/41388_2020_1311_Fig1_HTML.png)
HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene
Aberrant binding of mutant HSP47 affects posttranslational modification of type I collagen and leads to osteogenesis imperfecta | PLOS Genetics
Aberrant binding of mutant HSP47 affects posttranslational modification of type I collagen and leads to osteogenesis imperfecta
![HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41388-020-1311-7/MediaObjects/41388_2020_1311_Fig2_HTML.png)
HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α | Oncogene
![Expression of HSP47, a collagen-specific chaperone, in normal and diseased human liver | Laboratory Investigation Expression of HSP47, a collagen-specific chaperone, in normal and diseased human liver | Laboratory Investigation](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Flabinvest.3700271/MediaObjects/41374_2005_Article_BF3700271_Fig1_HTML.jpg)